piRNAome — Human piRNA Database

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piRNAome

— piRNAs — families — 1U — loci — locus SNVs — de novo

piRNAome Database Overview

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Total piRNAs

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Families

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Known Clusters

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De Novo Clusters

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SNV Annotated

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Family Overlaps

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Ping-pong Pairs

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1U Primary

SNV Interpretation

Genomic Context

De Novo Cluster Tiers

Quality Distribution

Family Size Distribution

Source Databases

Isoform Confidence

Verification Status

Data Sources

Every annotation in piRNAome is traceable to a published external resource. Versions reflect the snapshot ingested for the current release.

piRNA Primary Sources

piRBase v3.0 — sequence-verified piRNAs, gold-standard IDs

piRNABank — sequence corpus, multi-species

piRNAdb v1.7.6 — curated piRNA catalog

piRNAQuest v2.0 — clinically-relevant piRNA collection

SNV Interpretation

dbSNP build 151 — common population variants (snp151Common)

ClinVar — clinical variant interpretations

REDIportal v3 — A-to-I RNA editing sites (TABLE1 hg38)

COSMIC v104 — somatic mutations (coding + non-coding, tumor + matched normal)

Genomic Annotations

GENCODE v49 — gene models (coding + ncRNA)

Dfam / RepeatMasker — transposable element families (hg38)

miRBase v22 — miRNA loci & mature sequences

UCSC hg38 / GRCh38 — primary assembly reference

Pipeline: sequence compilation across four piRNA databases → Bowtie2 / STAR genome verification on hg38 → multi-database family clustering → annotation pass (gene / TE / miRNA / SNV / RNA-editing / somatic) → de novo cluster discovery (per-chromosome Poisson model) → TE-aware sub-family splitting. All scripts are open source.

piRNAome Database Overview

Data Sources

Genome-wide piRNA Distribution Full Browser →